publication

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Targeting Sox18 delays breast cancer in mice

Jeroen Overman, Frank Fontaine, Emmanuelle Lesieur and Mat Francois from the UQ CCVB Transcriptional Regulation of Vessels Laboratory and their collaborators have discovered that breast cancer in a mouse model can be delayed by pharmacological targeting of the SOX18 transcription factor.

 

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Improved methods for generating blood vessel and heart cells from hPSCs

Dr Nathan Palpant and Clayton Friedman from UQ CCVBs Stem Cells and Cardiovascular Development Laboratory and their collaborators from the University of Washington School of Medicine in the USA, have developed an efficient protocol to differentiate human pluripotent stem cells into heart muscle cells (cardiomyocytes) and blood vessel cells (endothelium).
 
The method has been published in Nature Protocols (Vol 12 No 1, 2017).
 

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Researchers grow beating human heart cells

Nathan Palpant and colleagues at the Institute for Stem Cell and Regenerative Medicine in Seattle, USA have grown beating human heart cells from stem cells. Published in the latest issue of Development, the study discovered the optimal conditions required for growth of the three different cell types that form the heart, blood and blood vessels.

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Zebrafish lymphatics on the cover of G & D

Kaska Koltowska and colleagues from the Hogan lab have just published their work investigating mafba in embryonic lymphangiogenesis in the prestigious journal Genes & Development, where her image was chosen for the August cover.

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Ben's news and views published in Nature

Ben Hogan was invited by Nature to write a news and views article for this month's edition of the prestigious journal (04 June 2015). Co-written with Brian Black, the article reviews two recent studies of the cells that give rise to lymphatic vessels, revealing that precursors arise from unexpected sources, and demonstrating that the origins of this vasculature are more diverse than anticipated.

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